Pre-Clinical Seizure Model Experience
Pre-Clinical Seizure Model Experience
- As Chief of the Epilepsy Branch, assumed overall responsibility for the Anticonvulsant Screening Program (ASP) (1979-1984)
- Published only comprehensive review of the ASP in 1985 (#3-CV, p14, #38)
- Published an evaluation of the mechanisms of actions of anti-seizure drugs and the ASP in 2015 (#3CV, p12, #79)
- Monitors the ASP program closely; observes new changes in study sequence; communicates frequently with the program director in Utah
- Understands the meaning of validated and non-validated preclinical models and the implications for potential new anti-seizure drugs